Tilted mammalian cell colony propagation dynamics on patterned substrates

Coarsening dynamics of dewetting nanodroplets on chemically patterned substrates.

Mesoscopic hydrodynamic equations are solved to investigate coarsening dynamics of two interacting nanodroplets on chemically patterned substrates. The effects of different parameters such as the surface chemical pattern, the slip length, the profile of the disjoining pressure, the size of the droplets, and the contact angles on the coarsening are studied. Our results reveal that the presence o...

Buckle delamination on patterned substrates

Lithographic techniques applied to a substrate prior to film deposition can create areas of low interface adhesion surrounded by regions of high adhesion. If the film is under compression and if buckle delamination is nucleated, conditions can be controlled such that delaminations are confined to the patterned areas of low adhesion. When the area of low adhesion is a strip, the width of the str...

Minimal model of directed cell motility on patterned substrates.

Crawling cell motility is vital to many biological processes such as wound healing and the immune response. Using a minimal model we investigate the effects of patterned substrate adhesiveness and biophysical cell parameters on the direction of cell motion. We show that cells with low adhesion site formation rates may move perpendicular to adhesive stripes while those with high adhesion site fo...

Modeling of Cell Motion on Patterned Adhesive and Deformable Substrates

CoSi2 heteroepitaxy on patterned Si(100) substrates

The influence of starting surface topography on the nucleation and growth of epitaxial silicide layers was investigated. CoSi2 layers were grown via the template technique on one-dimensionally patterned Si~100! substrates. These substrates contained mesa stripes, running parallel to Si@011#, and exhibited either a number of Si $hkl% facets, or ‘‘smoothly varying’’ sinusoidal profiles. Conventio...